The biology of what
remains unresolved

Two active lines of work, both centered on the same underlying question: what changes when a cell's epigenetic state is reprogrammed, and which of those changes are causal to aging rather than correlated with it.

The pace of longevity research creates pressure to treat findings as more conclusive than the evidence supports. Mechanisms get described as established before causal structures are resolved. VECVO exists to examine what remains unresolved — each paper starts from a specific open question, works through the primary literature, and states a position with explicit acknowledgment of where evidence is incomplete.

Alice Krant

Founding Researcher

Independent researcher focused on epigenetic reprogramming and aging biology — partial/OSK reprogramming, epigenetic clocks, and the mechanisms underlying biological age reversal.

ORCID 0009-0006-2567-1734 Academic site contact@vecvo.com @alicekrant.bsky.social

Open to collaboration with researchers, labs, and funders working on epigenetic reprogramming, aging biology, or related computational methods.